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KMID : 0191120230380350266
Journal of Korean Medical Science
2023 Volume.38 No. 35 p.266 ~ p.266
Reliability and Validity of the Korean Version of the Gout Impact Scale
Kim Min-Jung

Kim Ju-Yeon
Jennifer Jooha Lee
Moon Ki-Won
Shin Ki-Chul
Abstract
Background : The Gout Impact Scale (GIS), part of the Gout Assessment Questionnaire 2.0, measures gout-specific health-related quality of life (HRQOL). This study aimed to translate the GIS into Korean and validate the Korean version (K-GIS) using generic HRQOL measures.

Methods : The GIS was translated into Korean and back-translated into English. We asked patients aged 18 years or older who met the 2015 gout classification criteria to fill out the questionnaires (from January 2022 to June 2022); the K-GIS (5 scales [0?100 scores each]), along with the Korean version of Health Assessment Questionnaire (HAQ) and EuroQol-5 dimension (EQ-5D). We investigated the internal consistency, construct validity, and discriminative validity for gout characteristics of K-GIS. The K-GIS form was administrated to patients 4 weeks later to assess the test-retest reliability using the intraclass correlation coefficient (ICC).

Results : One hundred patients completed the questionnaire. The mean ¡¾ standard deviation age of the patients was 53.0 ¡¾ 15.1 years, and 99.0% of the patients were men. All scales had high degree of internal consistency (Cronbach¡¯s ¥á = 0.59 to 0.96) and test-retest reliability (n = 18, ICC = 0.83 to 0.94, all P < 0.001), except for unmet gout treatment needs. Weak-to-moderate correlations were observed between the K-GIS scales and HAQ or EQ-5D (r = 0.21 to 0.46). The K-GIS scores were significantly higher in the presence of bone erosion, absence of urate-lowering therapy, serum urate levels > 6 mg/dL, frequent gout flares in the past year, and fewer comorbidities. In contrast, neither the HAQ nor the EQ-5D could discern these subsets of patients.

Conclusion : The K-GIS is a reliable and valid HRQOL measure for patients with gout. Higher K-GIS scores were associated with clinical characteristics leading to unfavorable outcomes, which were not demonstrated by the HAQ and EQ-5D.
KEYWORD
Gout, Gout Impact Scale, Health-Related Quality of Life, Patient-Reported Outcome
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